When compared with no treatment, patients who received ethinyl estradiol 50 μg and cyproterone acetate 2 mg with cyproterone acetate 20 mg on days 5 to 20 of the menstrual cycle for 1 year had a significant increase in their percentage of anagen hairs with trends toward a larger shaft diameter of full anagen hairs and a decreased number of hairs that were less than 40 microns (Peereboom-Wynia et al., 1989). A 12-month randomized control trial of 66 women compared treatment with topical minoxidil 2% plus an oral contraceptive (ethinyl estradiol 30 μg + gestodene 75 μg) with treatment with cyproterone acetate 50 mg plus an oral contraceptive (ethinyl estradiol 35 μg + cyproterone acetate 2 mg) and demonstrated that treatment with cyproterone was more effective in hyderandrogenic patients but otherwise less effective (Vexiau et al., 2002). Side effects of cyproterone acetate include weight gain, breast tenderness, and a decreased libido (Kelly et al., 2016). Hepatotoxicity and development of multiple meningiomas may occur when doses exceed 25 mg daily (Medicines and Healthcare products Regulatory Agency, 2009). Cyproterone acetate is used widely in Europe and Canada, either in an isolated form or in combination with ethinyl estradiol, but it is only available in the United States as an orphan drug for the treatment of hirsutism (Carmina and Lobo, 2003, Jurzyk et al., 1992, Kelly et al., 2016). Cyproterone acetate is classified as pregnancy category X.

No one wants to lose their hair, but for a woman it is particularly distressing. While men can look perfectly presentable — even sexy — with their exposed scalp, no such options exist for the 30 million American women who grapple with thinning tresses. Dr. Maria Colavincenzo, a dermatologist at Northwestern University Feinberg School of Medicine, has a practice that specializes in preserving those precious strands — especially in cases of androgenetic alopecia, a hereditary condition that causes hair loss, mainly on the top and crown of the scalp. Without an appointment, she answered some of our questions:


Spending over a decade rigorously researching natural alternatives to a drug that negatively impacted his libido for seven years, Tsetis and his team reverse engineered the formula of a leading pharmaceutical only using patented sourced supplements. What they produced was a tested and proven hair health product that is now helping millions across the country avoid or actively cure for hair loss.
Visit your doctor. First and foremost, you need to understand the cause of your thinning brows in order to know how to address them. Your doctor can check for underlying conditions like hypothyroidism, hormonal imbalance and vitamin deficiency. Your doctor can also point you in the right direction for products that can help regrow or mask thinning hair. Visit a dermatologist for targeted advice and cosmetic options that are available to you.

Reduce stress. When you are stressed, your body starts shutting down processes that aren’t necessary for survival. This shutdown can occur with physical stressors, like surgery or an illness, and emotional stress, which often manifests as physical symptoms. Loss may occur up to three months after the stressful event and may take another three to grow again.[24]


Androgenetic alopecia, a type of hair loss commonly called male or female pattern baldness, was only partially understood until the last few decades. For many years, scientists thought that androgenetic alopecia was caused by the predominance of the male sex hormone, testosterone, which women also have in trace amounts under normal conditions. But while testosterone is at the core of the balding process, dihydrotestosterone (DHT) is now thought to be the main culprit.
*Photograph used with permission of the Journal of the American Academy of Dermatology. This photograph was published in the Journal of the American Academy of Dermatology, Vol. # 60, Gathers RC, Jankowski M, Eide M, et al. “Hair grooming practices and central centrifugal cicatricial alopecia,” 660-8. Copyright Elsevier (2009). Journal of the American Academy of Dermatology.   
There are a couple of other reasons why soy is a great choice too. For one, it is really good for you, protecting your cardiovascular health by reducing your LDL cholesterol levels. For another, soy is an easy, cost-effective choice. Instead of searching everywhere for quality herbal supplements you are unfamiliar with, you can simply add some soy milk to your diet or eat some tofu.
Sinclair Scale: The 5-point Sinclair Scale is a modified visual grading scale. Grade 1 is normal. This pattern is found in all girls prior to puberty, but in only half of women age 80 or over. Grade 2 shows a widening of the central part. Grade 3 shows a widening of the central part and thinning of the hair on either side of the central part. Grade 4 reveals the emergence of diffuse hair loss over the top of the scalp. Grade 5 indicates advanced hair loss. This grade is uncommon, occurring in less than 1% of women.
During and after pregnancy, estrogen levels may frequently rise and then dip back down quickly. This sudden dip is what leads to hair loss after giving birth, which can be normal and should stop as hormone levels balance again. If hair loss is accompanied by a myriad of other symptoms post pregnancy, there may be a deeper issue beyond normal hormone fluctuations, such as thyroid function. “But exhaustion, feeling down, difficulty losing weight, intense struggle to produce enough breast milk, and hair loss aren’t always just a normal part of having had a baby,” says Dr. Aviva Romm. If you are experiencing any of these issues post pregnancy, do talk to your doctor about what you are going through.
Sinclair Scale: The 5-point Sinclair Scale is a modified visual grading scale. Grade 1 is normal. This pattern is found in all girls prior to puberty, but in only half of women age 80 or over. Grade 2 shows a widening of the central part. Grade 3 shows a widening of the central part and thinning of the hair on either side of the central part. Grade 4 reveals the emergence of diffuse hair loss over the top of the scalp. Grade 5 indicates advanced hair loss. This grade is uncommon, occurring in less than 1% of women.
Other hair loss conditions that may be of an autoimmune nature that can involve the loss of eyebrows such as an underactive thyroid or vitiligo are termed “markers of underlying conditions”. It would be a trichologist’s responsibility to highlight these to the GP for further testing, these can also be investigated privately. In addition, there are conditions such as nutritional deficiencies like pernicious anaemia (unable to store B12) and of course anxiety and stress hair loss which can cause an overall reduction in the hair density. Patients attending with this concern often report that their general density is less dense.

Dozens of other causes of eyebrow loss are also possible including a variety of infectious, autoimmune and inflammatory conditions. Consultation with a dermatologist or hair transplant surgeon is recommended. I strongly advise consulting a dermatologist before proceeding to hair transplantation for women over 40 with new onset eyebrow hair loss after age 40.


Prostaglandins are modified forms of unsaturated fatty acids–those unsaturated or “essential” fatty acids (EFAs) that are also called Omega fatty acids. These EFAs cannot be produced by your body, but must be absorbed from our food. EFAs are naturally found in nut and seed oils in different compositions. EFAs have been shown to increase prostaglandin production in those with a deficiency (source, again).
I’m no Frida Kahlo, but since my teenage years, I’ve been blessed with thick, full eyebrows. But as soon as I turned 30, I noticed something was amiss. My beautiful brows were looking, let’s say, sparse. Every time my brow specialist handed me a magnified mirror after my monthly wax, it seemed I had more patchy spots. My low-maintenance morning routine—a quick brush-up and pencil fill-in—was suddenly taking up a lot more time. I found myself on a constant quest for the best brow powders, pencils, and gels, and started researching microblading in hopes of finding a solution.
Prostaglandins are modified forms of unsaturated fatty acids–those unsaturated or “essential” fatty acids (EFAs) that are also called Omega fatty acids. These EFAs cannot be produced by your body, but must be absorbed from our food. EFAs are naturally found in nut and seed oils in different compositions. EFAs have been shown to increase prostaglandin production in those with a deficiency (source, again).
Hormones don’t just affect your mood, they are also common culprits of hair loss. A hormone imbalance caused by thyroid disease, pregnancy, menopause, or hormone medication (like birth control pills) can lead to eyebrow loss. Thankfully, once you identify the source of the hormone imbalance and address the problem, your hair will likely grow back naturally.
These are only a few of the common myths heard by physicians and other hair loss specialists on a daily basis. The American Hair Loss Council suggests that you first have your hair loss diagnosed by a competent dermatologist who sees hair loss patients on a regular basis. Once you know the diagnosis you will have a better understanding of exactly which treatment option may be best for you.
EYES AND VISIONEARS, NOSE AND THROATSKIN, HAIR, NAILSHEART AND VESSELSKIDNEYS AND URINARY TRACTBLOOD AND IMMUNITYLIVER AND GALLBLADDERLUNGS AND AIRWAYSUPPER AND LOWER LIMBWOMEN’S HEALTH AND PREGNANCYWOMEN’S HEALTHKIDS HEALTHMEN’S HEALTHABCD – FIRST AID: INJURIES, POISONINGNEWBORNS BABIESHORMONES AND METABOLISMMEDICATION, SUPPLEMENTSMEDICAL TERMINOLOGYNUTRITIONSURGERY AND OTHER PROCEDURES
DLE is an autoimmune condition and is the most common form of chronic cutaneous lupus erythematosus.[35] Clinically, the lesions start as discoid erythematous patches which then develop into plaques with follicular plugging and scaling. Eyelid findings include blepharitis, lid scarring, entropion, and ectropion. Scaly plaques on the eyelids with loss of hair follicles results in madarosis[60] [Figure 3]. Numerous studies have reported the mimicking of a chronic blepharitis by DLE.[35,61–63] A high index of suspicion is necessary in such cases, where the diagnosis is very often delayed by months to years.[35] Biopsy with histopathological examination should be done to confirm the diagnosis. Treatment with hydroxychloroquine results in a regrowth of the eyelashes.[61]
Growth on Eyebrows – Some common growths on brow aresa such as warts or any unusual growth could hamper eyebrow growth. Skin growth cause a thick barrier that is shell like and it will make it impossible for eyebrows to penetrate them thus you will not have regrowth. Some of the common growths include moles, hemangiomas, seborrheic keratosis among many others.

“When I went in for my Bosley consultation, my senior counselor was the one who walked me through the procedure. He also had had the procedure done, and his results were phenomenal. And I was thinking, ‘Wow, if I can get that, that’s what I’m looking for.’ He really got it — he understood me. He understood what I went through, and that was really important to me.


Not only that, but plucking, waxing, or threading can also lead to permanent eyebrow loss, ingrown hairs, and infections. With repeated trauma to the hair follicle, your follicle can become damaged and scarred. If this occurs, your hair may never grow back again. Make sure to be extra careful to only pull out the hairs that you want to remove when you are plucking your brows. You should also wash your tweezers with alcohol before you start plucking or seek treatment at a reputable salon to prevent infections.
"Dr. Yaker and his staff are friendly, welcoming and professional. Everyone greets you with a smile and remembers your name. His offices and procedure rooms are always clean. Dr. Yaker is extremely knowledgable and willing to spend as much time answering questions and discussing options with his patients as they desire. I use Dr. Yaker's hair vitamins and shampoo and conditioner and have definitely seen positive results. So far, I have had two PRP treatments done by Dr. Yaker and he and his staff always take care of me and make me feel comfortable. I have recommended him to many of my friends and family. He's the best!"
So, if you have a similar paranoia—fear not! Losing strands is totally normal. But Dr. Wexler is quick to add that things like over-tweezing (it causes scarring to the follicles), waxing, severe weight-loss, stress, excessive touching, hormonal changes, and auto immune disease can cause irregular brow hair loss. If you believe your case may be extreme, it's best to see a specialist.
Information on this web site is provided for informational purposes only. The information is a result of years of practice experience by the author. This information is not intended as a substitute for the advice provided by your physician or other healthcare professional or any information contained on or in any product label or packaging. Do not use the information on this web site for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or homeopathic supplement, or using any treatment for a health problem. If you have or suspect that you have a medical problem, contact your health care provider promptly. Do not disregard professional medical advice or delay in seeking professional advice because of something you have read on this web site. Information provided on this web site and the use of any products or services purchased from our web site by you DOES NOT create a doctor-patient relationship between you and any of the physicians affiliated with our web site. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.
Eyebrow loss, also known as superciliary madarosis, can occur with a variety of medical conditions. Madarosis can affect one or both eyebrows with partial or complete hair loss. Infections, chronic skin disorders, hormone disturbances, autoimmune diseases and medications are among the many medical reasons for eyebrow loss. In most cases, identification and treatment of the underlying condition leads to regrowth of the eyebrows. Permanent eyebrow loss can occur with disorders that permanently damage the hair follicles.
Scalp hair loss may be a common complaint among men and women, but in my practice, loss of eyebrow hair is a major concern among my female patients. Because eyebrows frame the face, hair loss in this area can dramatically change one's appearance, and since eyebrow hair loss is not easily concealed, it can be, for some women, an even more devastating loss than scalp hair loss.  

Lichen planopilaris and frontal fibrosing alopecia inflammatory conditions, in which the inflammation destroys the hair follicle, can cause a scar or permanent hair loss (usually present as red patches with redness and scale around each hair follicle). In the very advanced stages, they may appear as smooth, bald patches where the hair follicles have been destroyed. Androgenetic hair loss is another non-scarring type. The most common type of hair loss, it is due to the complex interplay of genes, hormones, and age.
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