Hansen's disease, also known as leprosy, is an infection of the skin and nerves caused by the bacterium Mycobacterium leprae. The disease often affects the skin of the eyebrow region, leading to loss of sensation and permanent loss of the eyebrow hairs. There are numerous other rare and uncommon causes of eyebrow hair loss, including vitamin A toxicity, nutritional disorders and other dermatological disorders. If you experience loss of eyebrow hair, see your doctor to evaluate the cause and to discuss a treatment plan.
Another reason that you have thinning eyebrows might be low thyroid (which is called hypothyroidism. The thyroid gland controls the rate of use of energy sources, protein synthesis by producing thyroid hormones. I the thyroid gland does not produce enough hormones, you might feel tired, freeze in the cold, gain weight or lose your hair. The most common cause of hypothyroidism is iodine deficiency.
In your quest for perfectly maintained brows, you probably keep regular maintenance appointments on your calendar. Instead, you might want to embrace a more natural, hands-off approach. “The trauma inflicted on hair follicles during waxing, tweezing, and threading can lead to permanent follicular damage,” explains Dr. Umar. “Women who grew up in the height of the ’90s overplucked, pencil-thin brow trend have begun to notice the difficulty in growing thicker eyebrows after years of this habit.” 

Laser devices: Brushes, combs, and other hand-held devices that emit laser light might stimulate hair growth. These devices might make hair look more youthful in some people. Because the FDA classifies these products as medical devices, the products do not undergo the rigorous testing that medicines undergo. The long-term effectiveness and safety for these devices are not known.
Also, what we tend to forget is that while it’s easy for most women to recognize financial, emotional or overwhelm type stress, we also have internal metabolic and biochemical stresses like anemia, inflammation and nutrient deficiencies that we are often less aware of. Diet and exercise can also become stresses. It is well known that low calorie dieting or excessive exercise are commonly associated with hair loss.
Toxic alopecia occurs when there is a disruption of hair growth in the anagen phase. This usually occurs following chemotherapy and radiotherapy.[94] Radiotherapy for various types of ocular tumors, eyelid and choroidal tumors have been reported to produce madarosis.[95–97] Hair loss due to radiation is usually reversible, but may be permanent when the dose of radiation is in the range of 50 to 60 Gy.[94]
According to the new study, British scientists say they found over 200 genetic markers linked to hair loss. More specifically, the study focuses on male pattern baldness. This type of baldness, also known as male alopecia, is the most common form of hair loss in men. Researchers believe this affects as many as 30 to 50% of men by the time they reach the age of 50.
Hair loss in women isn't always as straightforward as it is in most men. In men, about 95 percent of all cases are caused by male pattern baldness. In women, however, hair loss can be triggered by a multitude of conditions and circumstances. During the consultation, Dr. Yaker utilizes specialized hair and scalp scanning technology to assess the distribution of hair loss, hair thickness, and how much hair is present in a particular area. It is important to note, that for women, a proper diagnosis begins with a process of elimination. More than one cause for the hair loss may coexist and need to be recognized or excluded. A comprehensive medical history, which includes a list of all medications, history of hair loss, a thorough scalp exam, a discussion of medical and skin disorders, and a complete nutritional evaluation will be needed. Blood work analysis may be required, and a scalp biopsy may also be performed if the cause of hair loss is uncertain or there is a concern for scarring alopecia.
Blepharitis is a chronic primary eyelid inflammation. It is fairly common in occurrence and being a condition with remissions and relapses, results in a decreased quality of life if adequate measures are not taken. Chronic blepharitis is the most common condition associated with madarosis.[10] Though there are various ways of classifying blepharitis, the most useful is the one proposed by Wilhelm,[24] wherein blepharitis can be classified based on whether there is a predominant involvement of the part of the eyelid anterior to the gray line (anterior blepharitis), or posterior to the gray line (posterior blepharitis). The gray line is an imaginary line dividing the eyelid into an anterior part consisting of the skin and muscle, and a posterior part consisting of the tarsus and conjunctiva.
Exercise is a key component of a healthy lifestyle. You’ll feel stronger and happier once you incorporate exercise into your daily routine. It also helps prevent some of the other symptoms of menopause, including mood swings, weight gain, and insomnia. All of these factors are important for maintaining hormonal balance, which promotes healthy hair growth.

Hair loss on the eyebrows can be partial where the hair falls off in patches or the eyebrow thins and shortens abnormally. It may occur on one side or both sides. It can also be complete where all the hair on one or both eyebrows are lost. These patterns of eyebrow hair loss can give some indication of the underlying cause even when there are no other symptoms. Some of these conditions may be specific to the eyebrows (the hair follicles and skin in that region) or can be an extension of problems affecting surrounding skin like the face, forehead or scalp.
MICHAEL REED, MD: Over-the-counter minoxidil, which is the brand Rogaine, is FDA approved. It's been shown to be effective in scientific studies. Propecia is the new drug on the block, and that probably is more effective. It's a pill that you take once a day, and that has been shown to slow down hair loss and grow hair in a significant number of individuals. Most of the other preparations that are heavily advertised or marketed are not proven to be effective.
Dutasteride is a 5-alpha-reductase inhibitor that binds both types I and II enzymes. Compared with finasteride, its inhibition of type II enzymes is three times more potent; its inhibition of type I enzymes is 100 times more potent (Clark et al., 2004). Dutasteride is not approved for the treatment of FPHL by the FDA, and ongoing studies on the efficacy of the inhibitor are promising but largely focus on male patients (Gupta and Charrette, 2014, Olsen et al., 2006). A study of women after 3 years of therapy showed that dutasteride may be more effective than finasteride in women under 50 years of age as measured by hair thickness (not hair density) at the center and vertex scalp (Boersma et al., 2014). One case report of a 46-year-old female with FPHL showed some response after 6 months of treatment with a dose of 0.5-mg dutasteride daily despite a minimal response to treatment with finasteride and minoxidil (Olszewska and Rudnicka, 2005). Data with regard to the treatment side effects in women is extremely limited. Dutasteride is classified as pregnancy category X because of teratogenicity and should have the same theoretical risk of breast cancer as mentioned in relation to finasteride (Kelly et al., 2016). 

Giorgos Tsetis: In the beginning, we left three factories because we didn't feel confident that they could do the job at our standard. These type of factories are sourcing the ingredients for you, but you have no clue where these ingredients are coming from. You don't know the efficacy, if they're clinically tested, and what about absorption? As a company, we decided to identify these root triggers that play a role in disrupting the hair growth cycle, then rigorously tested how we can target them and what specific ingredients solve for each trigger. Then, we developed individual partnerships with top suppliers all over the world that specialized in single ingredients that actually have that efficacy. We decided to source our own ingredients because we wanted to control the entire process. At least nine of the ten companies we consulted with said we couldn't do that, because the ingredients we chose to use were incredibly expensive. That's one main reason others can't do the work we do. For example, we purchase our primary ingredient for $600 per kilo, and you can buy the standard version of that ingredient in China for $30 per kilo. Same ingredients, but ours is clinically tested and proven to be effective. We only use patented ingredients, which made others think we're crazy, but creating the absolute best product is our top priority.
Telogen effluvium is a condition where a large number of hair follicles enter the resting phase known as telogen. As these hairs may fall off, it is not replaced with new hair at the same area and this leads to a bald patch on the eyebrows. A number of hormonal factors (like with hypothyroidism and pregnancy) may be responsible and it is also related to certain diseases, nutritional deficiencies, chronic medication use and even metal toxicity. It is now also known that stress can push many more hair follicles than normal into this phase.
The hormone imbalance known as hypothyroidism is a common cause of abnormal eyebrow thinning, especially in women; roughly 27 million Americans suffer from thyroid disease, and about 80 percent of them are women. Thinning eyebrows appear as a symptom of both hypothyroidism (underactive thyroid production) and hyperthyroidism (overactive thyroid production), alongside issues such as excessive fatigue, difficulty losing weight and constantly feeling cold. If your brows appear particularly thin around the edges, visit your doctor for a thyroid screening, which should include thorough blood work. With prescription medication, your eyebrows should fill back in over the ensuing months.
Scalp hair loss may be a common complaint among men and women, but in my practice, loss of eyebrow hair is a major concern among my female patients. Because eyebrows frame the face, hair loss in this area can dramatically change one's appearance, and since eyebrow hair loss is not easily concealed, it can be, for some women, an even more devastating loss than scalp hair loss.
Some cancer chemotherapy drugs cause temporary hair loss, which affects all body hair. Along with the loss of scalp hair, people undergoing chemotherapy also commonly lose their eyebrows and eyelashes. Chemotherapy drugs that frequently cause hair loss include paclitaxel, 5-fluorouracil, carboplatin, cisplatin, actinomycin-D, bleomycin, vincristine, cyclophosphamide, altretamine, etoposide, docetaxel and doxorubicin. Hair loss typically begins 2 to 3 weeks after the start of chemotherapy. Lost eyebrow hair regrows in the weeks to months following completion of treatment.

Giorgos Tsetis: I am an entrepreneur and have an engineering background that allows me to think in strategic ways to solve complex problems. Of course, I did have this very personal experience. But, to be honest with you, getting into this category wasn't directly a choice, it felt more like destiny. I say that, because their are literally millions who suffer from what I was suffering from. Aside from being a model, I owned an engineering company in New York, and business was steadily growing. The tipping point came when I found out the University of Washington published research that said my issue could cause permanent sexual dysfunction without the specific drug I was taking. That's when I panicked, reached out to my business partner and dear friend, and we begun to dig deeper into the issue. As we started diving deep, we recognized there was a tremendous white space.


Another cause of eyebrow hair loss is genetic predisposition. Many patients naturally have thinner eyebrows that run in their family. This is one of the biggest reasons patients seek our services. Medical conditions such as hypothyroidism, eczema, and alopecia areata (spot baldness) can also lead to brow hair falling out. It’s important to determine the cause of your condition to find an effective treatment. 

Low estrogen levels are most common during menopause, but it can happen to women at any age. As estrogen levels decline, the greater influence of testosterone shortens the growth phase, and the subsequent hair loss is usually gradual but can become noticeable over time. Hair loss caused by changing estrogen levels tends to be visible all over the scalp or evident in a widening part, rather than missing patches of hair or a horseshoe pattern as with male pattern baldness.


You basically have two major choices here: hormone replacement therapy (HRT) or phytotherapy (herbal remedies). You may wish there were more options, but there really are not. You can of course take other approaches to treating hair loss, but if low estrogen levels are one of the major causes of your hair loss, the results you will see treating the problem through other means are going to be quite limited if you are failing to treat the cause.
The different phases may last for varying periods of times from several years in anagen, to a few months in telogen or several weeks in anagen. Fortunately not all hair follicles are in the same phase at the same time. So the majority of the follicles will be in anagen phase, while a smaller amount will be in the catagen phase and a few follicles will be in the telogen phase. This ensures that there is always some hair present even when the follicle is not active and the hair is not growing.
After giving birth, reaching menopause years or experiencing other hormonal imbalances, it’s not uncommon for women to start losing hair. And while hair loss is a normal process (the American Academy of Dermatology estimates the average person sheds about 50-100 hairs a day), it’s also something that can be remedied by addressing underlying health and hormonal problems.

According to the International Society of Hair Restoration Surgery, since 2004, the number of female surgical hair restoration patients worldwide increased 24 percent. Modern surgical hair restoration procedures such as Follicular Unit Transplantation (FUT) and Follicular Unit Extraction (FUE) allow surgeons to take hair from the back of the head (genetically permanent hair zone) and transplant it to the areas where balding has occurred. The reason why the hair does not fall out once transplanted in its new location is because those hair follicles take on the same characteristics as the hair in the area where it originated, the genetically permanent zone. Both approaches result in lasting outcomes. In order to know if you are a candidate, Dr. Yaker will go over your medical history and examine your hair and scalp. He will determine if you have ample, good quality hair in the permanent hair zone in order to be able to relocate those hair follicles to the areas of hair loss.
Hair loss or baldness is a genetic trait, but unlike what you may have been told, it’s not necessarily passed down from your maternal grandfather. Medical science has come to learn that hair loss genes are actually passed down from both sides of the family, and they affect hair loss in both men and women. Hair loss genes may also skip generations and are utterly random in terms of which siblings (male or female) they will affect. The cause of hair loss for one family member may differ from that of another.

Hypoproteinemia[71] causes loss of hair due to premature onset of telogen. Loss of eyebrow hair has been reported due to chronic zinc deficiency in a patient receiving only parenteral nutrition for 2 months.[26] Acrodermatitis enteropathica is an inherited disorder of zinc deficiency which shows loss of eyebrows and lashes in addition to cutaneous manifestations.[72,73] Biotin deficiency can result in encephalopathy, neurological disorders, skin desquamation, and loss of eyebrows and eyelashes.[74] Iron deficiency may be a possible cause for diffuse telogen hair loss; its exact role however is subject to speculation.[75]
×