A new entity variously called as trichodysplasia spinulosa,[128] trichodysplasia of immunosuppression,[129] and cyclosporine-induced folliculodystrophy[130] has been described in immunocompromised patients, usually organ transplant recipients on immunosuppression. It involves the development of alopecia predominantly of the face with indurated spinous papules. There is a profound loss of eyebrows[131] and sometimes eyelashes. The histopathologic picture is that of abnormal follicles with hyperkeratotic infundibula and absence of normal hair shafts. The inner root sheath epithelium showed proliferation in the cells and dystrophic trichohyaline granules. Electron microscopy of skin showed presence of intracellular viral particles.[132] This entity has lately been reported in immunosuppressive states in patients without organ transplantation such as leukemias and lymphoma.[133–136] van der Meijden et al. described the discovery of a new polyoma virus in a patient with trichodysplasia spinulosa.[131] Histopathological examination can reveal the diagnosis. A recent simple pull-test wherein the spicules can be plucked and examined under the microscope for inner root sheath keratinization has been described.[136] Some successful treatments described are cessation of cyclosporine therapy[130] and oral valganciclovir[137,138] and topical cidofovir.[131]


Over-plucking or nutrient deficiency can be easily solved on your own with behavioral changes and nutritional supplements, but if you suspect that your thinning eyebrows are caused by a health problem, please see a doctor right away for treatment. Do not attempt to address hypothyroidism, eczema, or alopecia areata without the guidance of a medical professional.
Hi sir my name is azad alam i have eyebrow loss problem from many days ago.first had loss my hear and beard after some time everything wil have don.but some days later my eyebrow was beining loss.then i have use to start (rogan e jarari) this humdard madicin after this use madicine eyebrow was be improve.but after sometime problem have statr this problem till that.so please tell me any cure about this.
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The WHI was a very large, very prominent long-term study which looked at the health effects of HRT. While the study did find a few benefits (women who used HRT had fewer hip or bone fractures and were less likely to develop colorectal cancer), it found a number of risks, including an increased chance of heart attack, stroke, cancer, and blood clots. 

Androgenetic alopecia, commonly called male or female pattern baldness, was only partially understood until the last few decades. For many years, scientists thought that androgenetic alopecia was caused by the predominance of the male sex hormone, testosterone, which women also have in trace amounts under normal conditions. While testosterone is at the core of the balding process, DHT is thought to be the main culprit. 

Optimal levels of estrogen help to grow full thick hair, while low estrogen levels lead to thin and stalled hair growth, which eventually leads to hair loss. Through the years, a women will go through various cycles of highs and lows in estrogen levels. Puberty is typically associated with high estrogen levels as a woman starts to cycle through menstruation. Pregnancy typically increases hormone production, but once the baby has been delivered the mother can experience a drop in estrogen levels, which can result in thinning and loss of hair. Typically, this corrects itself as the woman's body heals and hormonal regulation returns to normal.  The largest decline in estrogen levels is during menopause. Estrogen is secreted through the ovaries and adrenal glands. When a woman hits menopause, the ovaries’ estrogen production is significantly diminished, which puts an excess burden on the adrenals to produce it. However, as the adrenals are typically overburdened due to stress, symptoms of menopauses like hair loss and hot flashes occur prematurely and excessively for some. Nourishing the body and balancing stress levels will support gentle and graceful transitions.  
Giorgos Tsetis: Consumers are lost, and that's the sad part about it. You have a serious problem, you go on the internet and see thousands of products making similar claims, and you can't choose. Most likely, you're going to try the cheapest product with the most compelling claims, realize it doesn't work, and only add further stress. When an industry is not properly regulated, this is the result. Education is such a big component of what we do. Reverse engineering a solution requires a tremendous amount of time and research. What we did was connect all these dots reading hundreds of pages of scientific literature. Education, when it comes to this, is broken into education for the physicians and education for the consumers. It's always hard to educate, because what you're really doing is changing behavior. Slowly but surely, we're actively changing the mindset of physicians and consumers, evolving the way they view and treat hair loss. That is huge, and one of the key reasons Unilever invested in the company. What we did was raise the bar by introducing a new category in the medical channel that remained untapped. That's how we disrupted the market, where now you see hundreds of doctors using Nutrafol as a trusted alternative for men and women. We also have several writers in the company who imagine how we can make this world simple and digestible for people. We want consumers to make smart choices.

Microblading is a semipermanent way to fill in brows that looks more natural than permanent makeup or tattooing. “Microblading differs from tattooing and the traditional form of permanent makeup in that it is typically done by hand versus a machine and doesn’t go as deep into the skin,” explains Studabaker. “In the past, tattooing and traditional permanent makeup usually resulted in a solid line and the color could change significantly with time.”


Posterior blepharitis is characterized by either excessive foam in the tear film in the hypersecretory type, or plugging of the meibomian orifices in the obstructive type. Expression of the secretions reveals a turbid or toothpaste-like material.[32] If there is spillover inflammation of the anterior lid margin, there may be a loss of eyelashes.[33]
Over-plucking or nutrient deficiency can be easily solved on your own with behavioral changes and nutritional supplements, but if you suspect that your thinning eyebrows are caused by a health problem, please see a doctor right away for treatment. Do not attempt to address hypothyroidism, eczema, or alopecia areata without the guidance of a medical professional.

You may have thought you were one up on men in the biological war but not only testosterone-strong males experience hair loss. In fact (and unfairly), up to 50% of women will experience some form of hair loss in their lifetime. You might have heard that pregnancy, the contraceptive pill and menopause are possible causes of hair loss, but are they really? Well, yes and no. An understanding of why female hair loss happens and what role estrogen plays in hair growth may help to make this answer clearer.
It is important to understand the phases of hair growth which play an important role when in further understanding some of the causes of hair loss. During the active phase known as anagen the cells multiply at the follicle and push out to form the shaft. It is followed by a transitional phase known as catagen where the outer layer of the hair shrinks and it becomes attached to the root. Thereafter there is a resting phase known as telogen where there is no growth or changes in the hair.
Sara Gottfried, MD is the New York Times bestselling author of the new book, Younger: A Breakthrough Program to Reset Your Genes, Reverse Aging, and Turn Back the Clock 10 Years. Her previous New York Times bestsellers are The Hormone Cure and The Hormone Reset Diet. After graduating from Harvard Medical School and MIT, Dr. Gottfried completed her residency at the University of California at San Francisco. She is a board-certified gynecologist who teaches natural hormone balancing in her novel online programs so that women can lose weight, detoxify, and slow down aging. Dr. Gottfried lives in Berkeley, CA with her husband and two daughters.
What she doesn’t mention is how to regrow your brows after chemo-related brow loss! If you have recently undergone chemotherapy, your brows may be a bit wonky in the beginning, but you still want them, right? They are the frame for your beautiful face. Every October we host a “Buy One Give One for the Cure” campaign, where for every bottle of WINK  sold, we donate one to a cancer survivor. If that’s you, shoot us an email so we can get you hooked up.
Karen Hellesvig-Gaskell is a broadcast journalist who began writing professionally in 1980. Her writing focuses on parenting and health, and has appeared in “Spirituality & Health Magazine" and “Essential Wellness.” Hellesvig-Gaskell has worked with autistic children at the Fraser School in Minneapolis and as a child care assistant for toddlers and preschoolers at the International School of Minnesota, Eden Prairie. 

The role of estrogen and progestogen drugs in the treatment of hair loss and growth is also unclear. Estrogen is made when androstenedione or testosterone are modified by the enzyme aromatase. It is synthesized in the ovary and other peripheral tissues and then travels to its receptors, some of which are located in scalp hair follicles (Thornton et al., 2003a, Thornton et al., 2003b). At the scalp follicle, estradiol has been reported to induce aromatase activity (Hoffmann et al., 2002). Estrogen has been hypothesized to have a protective role against hair loss on the basis of the observation that patients with lower estrogen levels during menopause, postpartum, or treatment with aromatase inhibitors or selective estrogen receptor modulators are more likely to develop FPHL (Atanaskova Mesinkovska and Bergfeld, 2013, Park et al., 2014). Another supporting observation is that in the frontal hairline of women, which tends to be spared with FPHL, there is a higher level of aromatase enzyme when compared with the rest of the scalp (Levy and Emer, 2013). This variation in hair loss could be the result of locally increased levels of estradiol or decreased levels of testosterone and DHT that is secondary to greater amounts of conversion.


Hair loss on the eyebrows can be partial where the hair falls off in patches or the eyebrow thins and shortens abnormally. It may occur on one side or both sides. It can also be complete where all the hair on one or both eyebrows are lost. These patterns of eyebrow hair loss can give some indication of the underlying cause even when there are no other symptoms. Some of these conditions may be specific to the eyebrows (the hair follicles and skin in that region) or can be an extension of problems affecting surrounding skin like the face, forehead or scalp.
Inflammation can play into thyroid related hair loss as can increased oxidative stress when the cause of the low thyroid is Hashimoto’s or autoimmunity. Immune activation in Hashimoto’s increases both of these additional causes of hair loss. As well it’s not uncommon to have multiple nutrient deficiencies when you have a low thyroid ranging from iron to B12 to a host of minerals including zinc and selenium. 

The process takes about two hours to complete, but you’ll need to go in for a touch up about once a year after the initial appointment (and possibly a second follow-up). Microblading costs between $500 and $1,000, and the results should last for one to three years. Your natural brow hair will continue to grow, but you likely won’t need to get waxed as often. “Most people find their regular maintenance decreased because they have the shape they want after microblading,” Studabaker says.
Various techniques have been described over the years. Nylon implants were used by some people. Now, they are banned in many countries because of sequelae-like scarring and infection. Follicular unit transplantation has been found to give very good results[195] and is now the procedure of choice for most types of hair transplantation. The details of the procedure with respect to eyebrow and eyelash reconstruction will be discussed here.
Furthermore, Penn dermatopathologists developed an even more advanced method called the HoVert technique for diagnosing hair loss and other disorders from a scalp biopsy. The technique uses a unique horizontal and vertical testing approach that provides a greater amount of information to the referring dermatologist than standard industry longitudinal scalp biopsies.
If you’re in good health but would like your brows to be a bit fuller, you’ve got plenty of options. Massage a bit of moisturizing coconut oil into your eyebrows about three times weekly, to make for healthier, shinier and more eye-catching hair. Eyebrow pencils remain an effective choice as a go-to filler; go a shade lighter than your brows for a natural look. To shake things up a bit, opt for a brow shadow. These powders, which look like eye shadow, go on with a brush and fill in thin or patchy brows with a soft and subtle fullness.
Medicines may also help slow or prevent the development of common baldness. One medicine, minoxidil (brand name: Rogaine), is available without a prescription. It is applied to the scalp. Both men and women can use it. Another medicine, finasteride (brand name: Propecia) is available with a prescription. It comes in pills and is only for men. It may take up to 6 months before you can tell if one of these medicines is working.

There are a lot of myths out there about balding men. One of them is that men with MPB are more virile and have higher levels of testosterone. This isn’t necessarily the case. Men with MPB may actually have lower circulating levels of testosterone but higher levels of the enzyme that converts testosterone to DHT. Alternately, you may simply have genes that give you hair follicles that are highly sensitive to testosterone or DHT.
Atopic dermatitis is a form of eczema that causes red, itchy patches of skin. Involvement of the skin around the eyes can lead to swelling, skin inflammation and loss of the eyebrow hairs, according to the National Institute of Arthritis and Musculoskeletal and Skin Diseases. Skin-irritating cosmetics and soaps may aggravate atopic dermatitis. The eyebrows often regrow when the condition becomes inactive.

Menopause is a natural biological process that all women experience at some point in their lives. During this time, the body goes through numerous physical changes as it adjusts to fluctuating hormone levels. Many women have unpleasant symptoms during menopause, including hot flashes, mood swings, and insomnia. Hair loss is another common occurrence.


Alopecia areata is a patchy hair loss associated with immune disturbances. In this condition the immune system attacks the hair follicles thereby impairing hair growth. It is more likely to occur in people with other immune-related disorders and has also been linked to psychological stress as well as with certain drugs like some types of ARVs used for HIV treatment. Alopecia areata does not only affect the scalp as commonly thought. The eyebrows and beard area, as well as hairy parts anywhere on the body may be affected.
What’s more likely is that telogen effluvium is at play (again). In addition to hormone fluctuations, this type of hair loss happens when there is a drastic dip in protein in the diet or sudden weight loss. For example, if you are sick and can only consume liquids for a month. “If you have protein levels that drop dramatically, your hair follicles go into hibernation, and you can see sudden acute hair loss that shows up three to six months later,” says Dr. Katta.
According to the International Society of Hair Restoration Surgery, since 2004, the number of female surgical hair restoration patients worldwide increased 24 percent. Modern surgical hair restoration procedures such as Follicular Unit Transplantation (FUT) and Follicular Unit Extraction (FUE) allow surgeons to take hair from the back of the head (genetically permanent hair zone) and transplant it to the areas where balding has occurred. The reason why the hair does not fall out once transplanted in its new location is because those hair follicles take on the same characteristics as the hair in the area where it originated, the genetically permanent zone. Both approaches result in lasting outcomes. In order to know if you are a candidate, Dr. Yaker will go over your medical history and examine your hair and scalp. He will determine if you have ample, good quality hair in the permanent hair zone in order to be able to relocate those hair follicles to the areas of hair loss. 

"Dr. Yaker and his staff are friendly, welcoming and professional. Everyone greets you with a smile and remembers your name. His offices and procedure rooms are always clean. Dr. Yaker is extremely knowledgable and willing to spend as much time answering questions and discussing options with his patients as they desire. I use Dr. Yaker's hair vitamins and shampoo and conditioner and have definitely seen positive results. So far, I have had two PRP treatments done by Dr. Yaker and he and his staff always take care of me and make me feel comfortable. I have recommended him to many of my friends and family. He's the best!"
But there’s load of hope! Just know it takes time and first and foremost it takes knowing the cause of the hair loss. That’s the only way to get on top of the issue. The type of hair loss you have (all over, patchy, thinning, losing only at temples, lack of new hair growth after shedding, etc.) points to the underlying cause of your shedding locks. So always start there.
Another reason that you have thinning eyebrows might be low thyroid (which is called hypothyroidism. The thyroid gland controls the rate of use of energy sources, protein synthesis by producing thyroid hormones. I the thyroid gland does not produce enough hormones, you might feel tired, freeze in the cold, gain weight or lose your hair. The most common cause of hypothyroidism is iodine deficiency.
It’s precisely because vitamins and minerals are SO critical to hormonal healing—and to healing the devastating side effects that come with it, like thinning hair—that I created the FLOLiving Balance Supplements. The supplement industry has very little oversight and I saw so many women waste money on supplements that at best didn’t work and at worse contained dangerous ingredients.

A. I'd say 25 percent get very good results. For another group, it just means that the situation is not getting worse, which no one ever considers a success. If you are thinking about it, you should start early. Minoxidil is not for everyone. … It can take at least six months to work — which doesn't fit most patients' time frames. It can stimulate facial hair or cause a rash on the scalp. It's not a miracle, but it's the only FDA-approved medication we have and it's been that way for 30 years. These are things we struggle with.
When you see more hair in the shower drain, in your hair brush or your ponytail holder goes around an extra time all of a sudden this is typically low thyroid, high stress or low estrogen. It can also be the increased inflammation or oxidative stress or as a result of nutrient deficiencies especially anemias (low iron, B12, etc.). Let’s dig into each of these.

Women using oestrogen supplementation or taking birth control pills will also experience hair loss when they cease supplying their body with extra oestrogen. These forms of hair loss may be temporary but this, however, does not mean that there is no link between oestrogen and permanent hair loss. Scientists have noted up to 30 hormones that could play a role in female pattern hair loss – the genetic kind of hair loss – and oestrogen, whilst poorly explored, may be one of them. It’s alright if the excess hairs are the ones that are lost but when normal hair falls out, there’s a problem.
Dutasteride is a 5-alpha-reductase inhibitor that binds both types I and II enzymes. Compared with finasteride, its inhibition of type II enzymes is three times more potent; its inhibition of type I enzymes is 100 times more potent (Clark et al., 2004). Dutasteride is not approved for the treatment of FPHL by the FDA, and ongoing studies on the efficacy of the inhibitor are promising but largely focus on male patients (Gupta and Charrette, 2014, Olsen et al., 2006). A study of women after 3 years of therapy showed that dutasteride may be more effective than finasteride in women under 50 years of age as measured by hair thickness (not hair density) at the center and vertex scalp (Boersma et al., 2014). One case report of a 46-year-old female with FPHL showed some response after 6 months of treatment with a dose of 0.5-mg dutasteride daily despite a minimal response to treatment with finasteride and minoxidil (Olszewska and Rudnicka, 2005). Data with regard to the treatment side effects in women is extremely limited. Dutasteride is classified as pregnancy category X because of teratogenicity and should have the same theoretical risk of breast cancer as mentioned in relation to finasteride (Kelly et al., 2016).

That's why I've designed a system I call The Gottfried Protocol, a step-by-step, integrative approach to natural hormone healing that emphasizes lifestyle design first and foremost. It's based on decades of research, my education at Harvard Medical School, my own experiences with hormonal imbalances, my belief in peer-reviewed, well-performed randomized trials to support my recommendations, and what I've learned from patients over the past 20-plus years of practicing medicine. The Gottfried Protocol engages only the top hierarchy of scientific evidence and has been proven in scores of women in my practice.
Tames and Goldenring described a case of bilateral loss of eyebrows and eyelashes in a patient with AIDS-related complex who had smoked crack cocaine. This has been attributed to hot vapors during the process of smoking, and which therefore caused singeing of the brows and lashes. There was a complete reversal once the patient abstained from cocaine.[93]
Madarosis is a clinical sign that has become pathognomonic of leprosy in countries like India. However, this apparently benign clinical sign has wider ramifications in many systemic and dermatological disorders. Hence, establishing a proper diagnosis and appropriate management is mandatory. Though management of the primary disease results in regrowth of eyebrows and eyelashes, many require surgical management. Thus, the management of a patient with madarosis requires a coordinated effort from the dermatologist, ophthalmologist, internist, and reconstructive surgeon.
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